Reaktion #8397

Reaktionsgleichung

5-amino-1-(2-phenylethyl)-1H-pyrazole-4-carboxylic acid

urea

→

title compound

Ausbeute 105.0%

6-Hydroxy-1-(2-phenylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ol

Ausbeute 105.0%

Lösungsmittel

water

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturcooled
2. 2
   Filtrationfiltered
3. 3
   Waschenwashed with water

Vorschrift

A mixture of 5-amino-1-(2-phenylethyl)-1H-pyrazole-4-carboxylic acid (1.87 g, 8.1 mmol) and urea (1.46 g, 24 mmol) was heated at 180° C. for 5 h, cooled and the resulting solid suspended in boiling water, filtered and washed with water to give the impure title compound (2.18 g, 105%,) as a cream solid.

Quelle