Reaktion #834776

Reaktionsgleichung

(2-amino-5-chlorophenyl)(2-chlorophenyl)methanone

sodium borohydride

→

expected product

Ausbeute 107.3%

(2-amino-5-chlorophenyl)(2-chlorophenyl)methanol

Ausbeute 107.3%

Lösungsmittel

ethyl acetate

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Waschenwashed with water
2. 2
   TrocknenThe organic phase is dried over anhydrous sodium sulfate
3. 3
   Einengenconcentrated

Vorschrift

To 20 g of (2-amino-5-chlorophenyl)(2-chlorophenyl)methanone dissolved in 80 ml of ethanol are introduced portionwise 8.6 g of sodium borohydride, and the mixture is left for 18 hours at room temperature. The reaction medium is taken up in ethyl acetate and washed with water. The organic phase is dried over anhydrous sodium sulfate and concentrated to give 21.63 g of the expected product.

Quelle