Reaktion #83407

Reaktionsgleichung

3-thiophenemethanol

sodium hydride

2,6- dichloro-4-methylmercaptopyridine

→

2-chloro-4-methylmercapto-6-(3-thienylmethyloxy)pyridine

Lösungsmittel

tetrahydrofuran

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.ADDITIONwas added

Vorschrift

To a solution containing 3-thiophenemethanol (0.56 g, 0.0041×1.2 mol) and sodium hydride (0.17 g, (ca.60% in mineral oil), 0.0041×1.05 mol) in tetrahydrofuran, 2,6- dichloro-4-methylmercaptopyridine (0.80 g, 0. 0041 mol) was added, and the resultant solution was refluxed for about 2 hours.

Quelle