Reaktion #83361

ord-6c4ba5c991764ddc92a5a0f1815b3425

Reaktionsgleichung

Nc1ccc(Sc2nc3ccccc3s2)cc1
2-(4-Aminophenylthio)benzothiazole
FC(F)(F)c1cc(N=C=S)ccc1Cl
4-chloro-3-trifluoromethylphenylisothiocyanate
→
FC(F)(F)c1cc(NC(=S)Nc2ccc(Sc3nc4ccccc4s3)cc2)ccc1Cl
title compound
FC(F)(F)c1cc(NC(=S)Nc2ccc(Sc3nc4ccccc4s3)cc2)ccc1Cl
1-[4-(2-Benzothiazolylthio)phenyl]-3-(4-chloro-3-trifluoromethylphenyl)thiourea

Edukte

Nc1ccc(Sc2nc3ccccc3s2)cc1
2-(4-Aminophenylthio)benzothiazole
FC(F)(F)c1cc(N=C=S)ccc1Cl
4-chloro-3-trifluoromethylphenylisothiocyanate

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

2-(4-Aminophenylthio)benzothiazole (10.0 moles, 2.6 g) and 4-chloro-3-trifluoromethylphenylisothiocyanate (10.0 moles, 2.4 g) were reacted according to procedure C to yield of the title compound, 1.5 g, 30%. Mass Spec (FD) 495. Calculated for C21H13ClF3N3S3 : C, 50.85 H, 2.64 N, 8.47. Found: C, 51.02; H, 2.71; N, 8.31.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05624937uspto-grants-1997_04