Reaktion #833518

Reaktionsgleichung

DMF

NBS

1b

1,2-di(2-ethylhexyloxy)benzene

NBS

→

4-bromo-1,2-di(2-ethylhexyloxy)benzene

Ausbeute 96.0%

Lösungsmittel

water

Reaktionsbedingungen

Aufarbeitung

1. 1
   WaschenThe organic layer was washed with a saturated LiCl solution and water
2. 2
   TrocknenAfter drying with MgSO4 the solvent
3. 3
   Sonstigewas removed under reduced pressure
4. 4
   workup.DISTILLATIONThe remaining oil was distilled (160° C./0.01 mmHg)

Vorschrift

Solid NBS (26.21 g, 0.147 mol) was added to an ice cold CH2Cl2 solution (250 mL) of 1b under N2 in the absence of light. Just enough DMF was added (30 mL) to dissolve the NBS. The reaction mixture was allowed to warm to room temperature and then stirred for 12 h. The mixture was then poured into water. The organic layer was washed with a saturated LiCl solution and water. After drying with MgSO4 the solvent was removed under reduced pressure. The remaining oil was distilled (160° C./0.01 mmHg) to yield 4-bromo-1,2-di(2-ethylhexyloxy)benzene (2b) in 96% yield as a colorless oil.

Quelle