Reaktion #833111

ord-6bfdd2a378e446b78161467224dbcc48

Reaktionsgleichung

O=C1CC2Cc3cc(N4CCC5(CC4)OCCO5)ccc3C2=NN1
2,4,4a,5-tetrahydro-7-(1,4-dioxa-8-azaspiro[4,5]dec-8-yl)-3H-indeno[1,2-c]pyridazin-3-one
O=c1cc2c(n[nH]1)-c1ccc(-n3ccnc3)cc1C2
2,5-dihydro-7-(1H-imidazol-1-yl)-3H-indeno[1,2-c]pyridazin-3-one
→
O=C1CC2Cc3cc(N4CCC(O)CC4)ccc3C2=NN1
2,4,4a,5-tetrahydro-7-(4-hydroxy-1-piperidinyl)-3H-indeno-[1,2-c]pyridazine-3-one

Edukte

O=C1CC2Cc3cc(N4CCC5(CC4)OCCO5)ccc3C2=NN1
2,4,4a,5-tetrahydro-7-(1,4-dioxa-8-azaspiro[4,5]dec-8-yl)-3H-indeno[1,2-c]pyridazin-3-one
O=c1cc2c(n[nH]1)-c1ccc(-n3ccnc3)cc1C2
2,5-dihydro-7-(1H-imidazol-1-yl)-3H-indeno[1,2-c]pyridazin-3-one

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

2,4,4a,5-tetrahydro-7-(1,4-dioxa-8-azaspiro[4,5]dec-8-yl)-3H-indeno[1,2-c]pyridazin-3-one, and 2,5-dihydro-7-(1H-imidazol-1-yl)-3H-indeno[1,2-c]pyridazin-3-one.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04602019uspto-grants-1986_07