Reaktion #83247

Reaktionsgleichung

3-benzoyl-2-thiophenecarboxylic acid

methylhydrazine

→

6,7-Dihydro-6-methyl-7-oxo-4-phenylthieno[2,3-d]pyridazine

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturrefluxed 3 hours
2. 2
   Temperaturcooled
3. 3
   Filtration30.7 g of the product filtered off

Vorschrift

A solution of 31.2 g (0.134 mol) of 3-benzoyl-2-thiophenecarboxylic acid in 400 mL of ethanol was treated with 9.3 (0.2 mol) of methylhydrazine at room temperature for 18 hours, refluxed 3 hours, cooled and 30.7 g of the product filtered off, mp 174-175.

Quelle