Reaktion #83074

Reaktionsgleichung

product

(+/-)-4-Bromo-2-(2,4-difluorophenyl)tetrahydrofuran

potassium thioacetate

acetonitrile

→

desired product

Ausbeute 76.7%

(+/-)-Ethanethioic acid S-[5-(2,4-difluorophenyl)tetrahydro-3-furanyl]ester

Ausbeute 76.7%

Lösungsmittel

ethyl acetate hexane

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeto give

Vorschrift

The title compound is prepared by the procedure of Example 5 using 1.9 g of product from Example 165, 0.866 g of potassium thioacetate and 30 ml of acetonitrile to give, after chromatography (silica gel: 5% ethyl acetate/hexane), 1.43 g of the desired product, as a mixture of isomers.

Quelle