Reaktion #8285

Reaktionsgleichung

1-benzyloxy-4-phenyl-butan-2-ol

pyridinium chlorochromate

→

title compound

Ausbeute 68.3%

1-Benzyloxy-4-phenyl-butan-2-one

Ausbeute 68.3%

Lösungsmittel

dichloromethane

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationThe mixture is filtered through a pad of SiO2
2. 2
   Einengenconcentrated

Vorschrift

To a solution of 1-benzyloxy-4-phenyl-butan-2-ol, (8.4 g, 32.8 mmol) in dichloromethane (400 mL) is added a mixture of pyridinium chlorochromate (14.1 g, 65.6 mmol) with SiO2 (14 g) and stirred for 3 h at room temperature. The mixture is filtered through a pad of SiO2 and concentrated to provide the title compound 5.7 g (68%) as a colorless liquid.

Quelle