Reaktion #82799

Reaktionsgleichung

2-nitrophenol

benzyl bromide

potassium carbonate

→

2-(Benzyloxy)nitrobenzene

Lösungsmittel

acetone

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturis heated
2. 2
   Temperaturunder reflux for 16 hours
3. 3
   Temperaturcooled
4. 4
   workup.ADDITIONpoured onto ice-dilute hydrochloric acid
5. 5
   Extraktionextracted with dichloromethane
6. 6
   SonstigeThe extract is dried
7. 7
   Sonstigeevaporated
8. 8
   Sonstigethe residue is crystallized from ether-hexane as pale crystals, m.p. <50° C.

Vorschrift

A stirred mixture of 2-nitrophenol (13.9 g, 0.10 mol), benzyl bromide (12.0 ml, 0.10 mol) and anhydrous potassium carbonate (30 g, 0.22 mol) in acetone (200 ml) is heated under reflux for 16 hours, cooled, poured onto ice-dilute hydrochloric acid, and extracted with dichloromethane. The extract is dried and evaporated and the residue is crystallized from ether-hexane as pale crystals, m.p. <50° C.

Quelle