Reaktion #82541

Reaktionsgleichung

triethylamine

oxalyl chloride

dimethyl sulfoxide

[1-(4-chlorophenyl)-1-cyclopentyl]methanol

→

1-(4-chlorophenyl)-1-cyclopentanecarboxaldehyde

Lösungsmittel

methylene chloride

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThis compound is prepared in a manner analogous to that of Step B of Example 4

Vorschrift

This compound is prepared in a manner analogous to that of Step B of Example 4, using 7.0 grams (0.055 mole) of oxalyl chloride, 9.5 grams (0.120 mole) of dimethyl sulfoxide, 10.5 grams (0.050 mole) of [1-(4-chlorophenyl)-1-cyclopentyl]methanol, and 25.5 grams (0.250 mole) of triethylamine in 175 mL of methylene chloride, yielding 1-(4-chlorophenyl)-1-cyclopentanecarboxaldehyde.

Quelle