Reaktion #82479

Reaktionsgleichung

phosgene

testosterone

→

Testosterone chloroformate

Lösungsmittel

toluene

tetrahydrofuran

Reaktionsbedingungen

Aufarbeitung

1. 1
   Einengenconcentrated under vacuum
2. 2
   Sonstigethe resulting residue vacuum dried for approximately 30 minutes (2.88 g)

Vorschrift

Testosterone chloroformate was prepared as follows. To a solution of testosterone (2 g, 7.0 mmol) dissolved in tetrahydrofuran (50 ml) was added a 1.93M solution of phosgene in toluene (33 ml). The resulting solution was stirred for 4 h at room temperature, concentrated under vacuum, and the resulting residue vacuum dried for approximately 30 minutes (2.88 g).

Quelle