Reaktion #824264

Reaktionsgleichung

2-Bromobenzyl bromide

2-Phenyl-morpholine

potassium carbonate

→

product

Ausbeute 63.0%

4-(2-Bromo-benzyl)-2-phenyl-morpholine

Ausbeute 63.0%

Lösungsmittel

acetonitrile

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationThe solution was filtered through Celite
2. 2
   Einengenconcentrated in vacuo
3. 3
   Sonstigeto afford a brown solid
4. 4
   SonstigePurification by flash chromatography

Vorschrift

1.877 g of 2-Bromobenzyl bromide and 1 g of 2-Phenyl-morpholine in 15 mL of acetonitrile were stirred at room temperature and 2.076 g of potassium carbonate was added. The reaction was stirred at room temperature overnight. The solution was filtered through Celite and concentrated in vacuo to afford a brown solid. Purification by flash chromatography afforded 1.052 g of product. 63% yield ES MS m/z 332

Quelle