Reaktion #823

Reaktionsgleichung

Brc1cccc(Br)n1

NC1CCOCC1

→

Brc1cccc(NC2CCOCC2)n

Lösungsmittel

C1COCCO1

Vorschrift

to 2,6-dibromopyridine (100 mg, 0.42 mmol), 4-Aminotetrahydropyran (42.7 mg, 0.42 mmol) in dioxane (3 mL) while bubbling N2 was added Xantphos (24.43 mg, 0.04 mmol), CS2CO3 (316 mg, 0.97 mmol) and palladium(II) acetate (9.48 mg, 0.04 mmol). This was heated in a microwave at 130 oC for 30 mins. A small peak corresponding to product was obseved. Discontinued

Quelle