Reaktion #82159

Reaktionsgleichung

1-aminomethyl-7-azabicyclo[3.3.0]octane

ethanol

→

1-Aminomethyl-3-oxa-7-azabicyclo[3.3.0]octane

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationThe catalyst is filtered off with suction
2. 2
   Einengenthe filtrate is concentrated
3. 3
   workup.DISTILLATIONdistilled

Vorschrift

2.8 g (12.1 mmol) of 1-aminomethyl-7-azabicyclo[3.3.0]octane are dissolved in 50 ml of ethanol and hydrogenated on 0.3 g of palladium-active charcoal at 100° C. and 100 bar. The catalyst is filtered off with suction and the filtrate is concentrated and distilled. Yield: 1.5 g (87% of theory) Boiling point: 70°-72° C./0.03 mbar.

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