Reaktion #82131

Reaktionsgleichung

2,6-di-tert-butyl-4-(2-nitrostyryl)phenol

→

4-(2-aminophenethyl)-2,6-di-tert-butylphenol

Ausbeute 199.1%

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationAfter filtering the catalyst
2. 2
   workup.DISTILLATIONdistilling off the solvent

Vorschrift

To a suspension of 2,6-di-tert-butyl-4-(2-nitrostyryl)phenol (16.4 g, 23.3 mmol) in ethanol (150 ml) was added a catalytic amount of 10% palladium carbon and the suspension was subjected to catalytic reduction at room temperature at 1-2.5 atms for 8 hrs and at 40° C. for 3 hrs. After filtering the catalyst, distilling off the solvent gave 4-(2-aminophenethyl)-2,6-di-tert-butylphenol (15.1 g, 100%) as a viscous oil.

Quelle