Reaktion #82110

Reaktionsgleichung

sulfuric acid

3-ethoxy-4-hydroxybenzaldehyde

aniline

Malonic acid

→

compound

Ausbeute 56.1%

3-ethoxy-4-hydroxycinnamic acid

Ausbeute 56.1%

Lösungsmittel

pyridine

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe crude crystals were obtained by filtration
2. 2
   Waschenwashed with water
3. 3
   Sonstigedried

Vorschrift

Malonic acid (1.56 g) and pyridine (3.0 ml) were placed in an egg-plant type flask (100 ml). Further, 3-ethoxy-4-hydroxybenzaldehyde (1.66 g) and aniline (30 μl) were added thereto and a reaction was performed at 55° C. for 3 hours. The reaction solution was acidified by adding dilute sulfuric acid. The crude crystals were obtained by filtration, washed with water, and then dried to obtain the above-identified compound (1.1 g, 56.1%) as a light yellowish crystal. Melting point: 157°-158° C.

Quelle