Reaktion #819942

Reaktionsgleichung

water

4-bromo-2-chloro-1-methylsulfanyl-benzene

mCPBA

→

title compound

Ausbeute 31.0%

4-Bromo-2-chloro-1-methanesulfonyl-benzene

Ausbeute 31.0%

Lösungsmittel

dichloromethane

dichloromethane

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeSeparate the organic layer
2. 2
   Waschenwash with aqueous saturated NaHCO3 (2×100 mL) and brine (100 mL)
3. 3
   TrocknenDry with MgSO4
4. 4
   Filtrationfilter
5. 5
   Einengenconcentrate in vacuo
6. 6
   WaschenWash the solid with ether (2×10 mL) and dichloromethane (10 mL)

Vorschrift

Dissolve 4-bromo-2-chloro-1-methylsulfanyl-benzene (4.8 g, 20 mmol) and mCPBA (20 g, 80 mmol) in dichloromethane (100 mL). Stir for 2 hours. Dilute with dichloromethane (300 mL) and water (100 mL). Separate the organic layer and wash with aqueous saturated NaHCO3 (2×100 mL) and brine (100 mL). Dry with MgSO4, filter and concentrate in vacuo. Wash the solid with ether (2×10 mL) and dichloromethane (10 mL) to give 1.7 g of the title compound (31%).

Quelle