Reaktion #81965

Reaktionsgleichung

4-mercapto-2-phenyl-pyrimidine-5-carboxylic acid phenethyl-amide

iodine

→

title compound

Ausbeute 71.5%

2-Phenethyl-6-phenyl-isothiazolo[5,4-d]pyrimidin-3-one

Ausbeute 71.5%

Reaktionsbedingungen

Vorschrift

Using the procedure of Example 20, 2.0 g (5.96 mmol) of 4-mercapto-2-phenyl-pyrimidine-5-carboxylic acid phenethyl-amide were treated with 1.66 g (6.56 mmol) of iodine to give 1.42 g of the title compound after recrystallization from isopropanol, mp 144°-147° C.

Quelle