Reaktion #81762

Reaktionsgleichung

2-(2,4,6-triiodophenoxy)-pentadecane

mesylate

3-nonanol

triiodophenol

potassium carbonate

2-(2,4,6-triiodophenoxy)-pentadecane

→

3-(2,4,6-Triiodophenoxy)-nonane

Ausbeute 67.3%

Lösungsmittel

—

hexanes

DMF

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeto provide a light brown oil

Vorschrift

The mesylate of 3-nonanol (11.5 g, 51.9 mmol), triiodophenol (24.5 g, 51.9 mmol) and potassium carbonate (7.18 g, 51.9 mmol) were reacted in dry DMF (200 ml) as per 2-(2,4,6-triiodophenoxy)-pentadecane except at an oil bath temperature of 87° C. for 16 hrs. The reaction was processed as for 2-(2,4,6-triiodophenoxy)-pentadecane to provide a light brown oil. Flash column chromatography (silica, hexanes) provided 3-(2,4,6-Triiodophenoxy)-nonane (20.9 g, 67%) as a clear viscous oil.

Quelle