Reaktion #81758

Reaktionsgleichung

2-methanesulfonyloxydecane

2,4,6-triiodophenol

potassium carbonate

2-(2,4,6-triiodophenoxy)-pentadecane

2-(2,4,6-triiodophenoxy)-pentadecane

→

2-(2,4,6-triiodophenoxy)-decane

Ausbeute 75.9%

Lösungsmittel

DMF

—

hexanes

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeto provide a light brown residue

Vorschrift

The 2-methanesulfonyloxydecane (14.8 g, 62.6 mmol), 2,4,6-triiodophenol (29.7 g) 62.9 mmol) and potassium carbonate (8.7 g, 63.0 mmol) were reacted in DMF (210 ml) as per 2-(2,4,6-triiodophenoxy)-pentadecane except at an oil bath temperature of 72° C. for 88 hrs. The reaction was processed as for 2-(2,4,6-triiodophenoxy)-pentadecane to provide a light brown residue. Flash column chromatography (silica, hexanes) provided 2-(2,4,6-triiodophenoxy)-decane (29.1 g, 75.9%) as a white solid.

Quelle