Reaktion #81586
ord-baf3153e0aee4c7b907510d1c5905477
Reaktionsgleichung
ethyl 4-(4-bromophenyl)butanoate
Compound C
ethyl 4-(4-bromophenyl)butanoate
ethyl (3-bromophenyl)acetate
ethyl 3-bromophenylacetate
Compound B
ethyl 3-bromophenylacetate
→
title compound
Ethyl 4-(3-bromophenyl)butanoate
Edukte
Reagenzien
Keine
Reaktionsbedingungen
Detaillierte Bedingungen
See reaction.notes.procedure_details.
Vorschrift
Employing the same general multistep preparation as for ethyl 4-(4-bromophenyl)butanoate (Compound C), 60 g (246 mmol) of ethyl (3-bromophenyl)acetate (Compound B) was converted into the title compound (oil) using 255 ml (255 mmol) of diisobutylaluminum hydride (DIBAL-H, 1M in hexane), 85.8 g (250 mmol) of (carbethoxymethylene) triphenylphosphorane and 1.7 g of 10% Pd/C.