Reaktion #815752

Reaktionsgleichung

product

2-Benzyl-8-methoxy-1,2,3,3a,8,8a-hexahydroindeno[1,2-c]pyrrole hydrochloride

→

desired product

Ausbeute 90.5%

8-Methoxy-1,2,3,3a,8,8a-hexahydro-indeno[1,2-c]pyrrole hydrochloride

Ausbeute 90.5%

Lösungsmittel

methanol

Reaktionsbedingungen

Vorschrift

The product from Example 5 (4.90 g) was hydrogenated with 2.45 g 20% Pd/C in 200 ml methanol at 3 atm, affording 3.17 g of the desired product, mp: 208-209° C. NMR (d6DMSO/D2O) δ 2.83 (m, 2H), 3.14-3.29 (m, 3H), 3.46 (dd, 1H), 3.55 (dd, 1H), 3.80 (s, 3H), 3.95 (m, 1H), 6,85 (d, 2H), 7.25 (t, 1H).

Quelle