Reaktion #8152

Reaktionsgleichung

2-chloro-5-nitropyridine

hydrazine hydrate

→

(5-nitropyridin-2-yl)hydrazine

Lösungsmittel

ethanol

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.ADDITIONAt the end of the addition
2. 2
   SonstigeThe named product precipitated from the reaction medium
3. 3
   Filtrationwas collected by filtration
4. 4
   Sonstigerecrystallized from ethanol

Vorschrift

To a solution of 2-chloro-5-nitropyridine (30 mmol, 5.0 g) in absolute ethanol was added a solution of hydrazine hydrate (320 mmol, 15.8 g) in ethanol using syringe pump. At the end of the addition, the reaction was refrigerated. The named product precipitated from the reaction medium, was collected by filtration, and recrystallized from ethanol.

Quelle