Reaktion #81167

Reaktionsgleichung

ethyl 2-butyl-4-(1-hydroxy-1-methylethyl)imidazole-5-carboxylate

t-butyl 4'-bromomethylbiphenyl-2-carboxylate

→

title compound

Ausbeute 65.3%

Ethyl 1-[(2'-t-butoxycarbonylbiphenyl-4-yl)methyl]-2-butyl-4-(1-hydroxy-1-methylethyl)imidazole-5-carboxylate

Ausbeute 65.3%

Reaktionsbedingungen

Vorschrift

Following a procedure similar to that described in Example 1(a), but using 0.92 g of ethyl 2-butyl-4-(1-hydroxy-1-methylethyl)imidazole-5-carboxylate (prepared as described in Preparation 8) and 1.28 g of t-butyl 4'-bromomethylbiphenyl-2-carboxylate, 1.23 g of the title compound were obtained as crystals, melting at 92°-93° C.

Quelle