Reaktion #806527

ord-28855e6d2af649ac9b55d25266f03852

Reaktionsgleichung

Nc1nc(-c2sccc2Cl)cs1
4-(3-chloro-2-thienyl)-1,3-thiazol-2-amine
O=S(=O)(Cl)c1c(Cl)cc(Cl)cc1Cl
2,4,6-trichlorobenzenesulfonyl chloride
→
O=S(=O)(Nc1nc(-c2sccc2Cl)cs1)c1c(Cl)cc(Cl)cc1Cl
title compound
O=S(=O)(Nc1nc(-c2sccc2Cl)cs1)c1c(Cl)cc(Cl)cc1Cl
2,4,6-Trichloro-N-[4-(3-chloro-2-thienyl)-1,3-thiazol-2-yl]benzenesulfonamide

Edukte

Nc1nc(-c2sccc2Cl)cs1
4-(3-chloro-2-thienyl)-1,3-thiazol-2-amine
O=S(=O)(Cl)c1c(Cl)cc(Cl)cc1Cl
2,4,6-trichlorobenzenesulfonyl chloride

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title compound was prepared from 4-(3-chloro-2-thienyl)-1,3-thiazol-2-amine and 2,4,6-trichlorobenzenesulfonyl chloride as described in the synthetic METHOD B to give a white solid (5.0 mg) with purity >90%. MS (pos) m/z 459.1, 461.1, 463.1.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07132436B2uspto-grants-2006_11