Reaktion #804816

Reaktionsgleichung

product

tert-Butyl 2-(3-(4-octylbenzyl)-2-oxoimidazolidin-1-yl)acetate

tert-butyl 2-(4-(4-octylphenyl)piperazin-1-yl)acetate

→

title compound

Ausbeute 46.0%

2-(3-(4-Octylbenzyl)-2-oxoimidazolidin-1-yl)acetic acid

Ausbeute 46.0%

Reaktionsbedingungen

Vorschrift

When the product of Step B was substituted for tert-butyl 2-(4-(4-octylphenyl)piperazin-1-yl)acetate in Example 9, Step F, the identical process afforded the title compound in 46% yield, as a colourless solid. 1H-NMR (CDCl3+CD3OD) 7.0 (m, 4H); 4.42 (s, 2H); 3.72 (s, 2H); 3.31 (m, 2H); 3.11 (m, 2H); 2.44 (t, 2H, J=7.8 Hz); 1.43 (m, 2H); 1.13 (m, 10H); 0.73 (t, 3H, J=7 Hz).

Quelle