Reaktion #8046

Reaktionsgleichung

( 10 )

4-(4-tert-butoxycarbonyl-1-piperazinyl)-methyl-6-(3-fluoro-4-methylphenyl)-2-isobutyl-2H-pyridazin-3-one

2-isobutyl-4-methanesulfonyloxymethyl-6-(4-trifluoromethylphenyl)-2H-pyridazin-3-one

tert-butyl 1-piperazinecarboxylate

→

title compound

Ausbeute 83.5%

4-(4-tert-butoxycarbonyl-1-piperazinyl)-methyl-2-isobutyl-6-(4-trifluoromethylphenyl)-2H-pyridazin-3-one

Ausbeute 83.5%

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigewere reacted

Vorschrift

Following the procedure of Example 1 (10), 2-isobutyl-4-methanesulfonyloxymethyl-6-(4-trifluoromethylphenyl)-2H-pyridazin-3-one and tert-butyl 1-piperazinecarboxylate were reacted to yield the title compound as a yellow oil (yield: 83.5%).

Quelle