Reaktion #80361

Reaktionsgleichung

N-[4-(4-piperidinomethyl-2-pyridyloxy) -cis-2-butenyl]-4-chlorobutyramide

3-mercapto-1,2,4-triazole

→

title compound

Ausbeute 56.0%

N-[4-(4-Piperidinomethyl-2-pyridyloxy)-cis-2-butenyl]-4-(1,2,4-triazol-3-ylthio)butyramide

Ausbeute 56.0%

Reaktionsbedingungen

Vorschrift

Following a procedure similar to that described in Example 34, but using N-[4-(4-piperidinomethyl-2-pyridyloxy) -cis-2-butenyl]-4-chlorobutyramide (prepared as described in Preparation 2) and 3-mercapto-1,2,4-triazole as starting materials, in relative proportions similar to those used in that Example, the title compound was obtained as a white powder, melting at 87°-89° C., in a 56% yield.

Quelle