Reaktion #80311

Reaktionsgleichung

4-nitroanthranilic acid

4-chloro-7-nitroquinazoline

4-chloro-7-nitroquinazoline

3-methylaniline

→

4-(3'-methylanilino)-7-nitroquinazoline

Reaktionsbedingungen

Vorschrift

Using an analogous procedure to that described in the portion of Example 1 which is concerned with the preparation of starting materials, 4-nitroanthranilic acid was converted into 4-chloro-7-nitroquinazoline. Using an analogous procedure to that described in Example 1 except that the reactants were stirred together at ambient temperature for 20 minutes, 4-chloro-7-nitroquinazoline was reacted with 3-methylaniline to give 4-(3'-methylanilino)-7-nitroquinazoline.

Quelle