Reaktion #80310

Reaktionsgleichung

6,7-dimethoxy-4-(3'-chloroanilino)quinazoline

sodium ethanethiolate

→

6,7-dihydroxy-4-(3'-chloroanilino)quinazoline

Ausbeute 68.0%

Reaktionsbedingungen

Vorschrift

Using an analogous procedure to that described in Example 4, 6,7-dimethoxy-4-(3'-chloroanilino)quinazoline was reacted with sodium ethanethiolate to give 6,7-dihydroxy-4-(3'-chloroanilino)quinazoline in 68% yield, m.p. 233°-235° C.

Quelle