Reaktion #8027

ord-41ba53391d074cb3803addfbb5300834

Reaktionsgleichung

COC1C(=O)NN=C(c2ccc(C)c(F)c2)C1=C=O
( 5 )
COC1C(=O)NN=C(c2ccc(C)c(F)c2)C1=C=O
6-(3-fluoro-4-methylphenyl)-4-methoxy-carbonyl-2H-pyridazin-3-one
O=C(O)c1cc(-c2ccccc2)n[nH]c1=O
4-carboxy-6-phenyl-2H-pyridazin-3-one
→
COC(=O)c1cc(-c2ccccc2)n[nH]c1=O
title compound
Ausbeute 98.9%
COC(=O)c1cc(-c2ccccc2)n[nH]c1=O
4-methoxycarbonyl-6-phenyl-2H-pyridazin-3-one
Ausbeute 98.9%

Edukte

COC1C(=O)NN=C(c2ccc(C)c(F)c2)C1=C=O
( 5 )
COC1C(=O)NN=C(c2ccc(C)c(F)c2)C1=C=O
6-(3-fluoro-4-methylphenyl)-4-methoxy-carbonyl-2H-pyridazin-3-one
O=C(O)c1cc(-c2ccccc2)n[nH]c1=O
4-carboxy-6-phenyl-2H-pyridazin-3-one

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    Sonstigewas reacted

Vorschrift

Following the procedure of Example 1 (5), 4-carboxy-6-phenyl-2H-pyridazin-3-one was reacted to yield the title compound as pale yellow crystals (yield: 98.9%).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07087606B2uspto-grants-2006_08