Reaktion #80183

Reaktionsgleichung

4′-Trifluoromethyl-biphenyl-2-carboxylic acid

thionyl chloride

→

title product

Ausbeute 99.0%

4′-Trifluoromethyl-biphenyl-2-carbonyl chloride

Ausbeute 99.0%

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturthe mixture was heated
2. 2
   Temperaturat reflux
3. 3
   Einengenthe mixture was concentrated under vacuum

Vorschrift

4′-Trifluoromethyl-biphenyl-2-carboxylic acid (25 g, 94 mmol) was combined with thionyl chloride (35 ml, 470 mmol) and the mixture was heated at reflux. After 2 h, the mixture was concentrated under vacuum to afford 26.5 g of the title product as a light yellow oil.

Quelle