Reaktion #80109

Reaktionsgleichung

[3-isopropyl-4-(1-methyl-cyclopropoxymethyl)-phenylethynyl]-trimethylsilane

Intermediate 165

[3-isopropyl-4-(1-methyl-cyclopropoxymethyl)-phenylethynyl]-trimethylsilane

potassium carbonate

→

4-Ethynyl-2-isopropyl-1-(1-methyl-cyclopropoxymethyl)-benzene

Lösungsmittel

methanol

Reaktionsbedingungen

Vorschrift

Using General Procedure E; [3-isopropyl-4-(1-methyl-cyclopropoxymethyl)-phenylethynyl]-trimethylsilane (Intermediate 165, 110.0 mg, 0.37 mmol) in methanol (6 mL) was treated with potassium carbonate (80.0 mg, 0.58 mmol) and stirred overnight at ambient temperature. The crude alkyne (84 mg, 100%) was used directly in the next reaction.

Quelle