Reaktion #800779

Reaktionsgleichung

(6-iododibenzo[b,d]furan-4-yl)triphenylsilane

(3-chlorophenyl) boronic acid

K2CO3

→

(6-(3-chlorophenyl)dibenzo[b,d]furan-4-yl)triphenylsilane

Ausbeute 21.0%

Lösungsmittel

toluene

water

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe organic layer was separated
2. 2
   Sonstigethe solvent was evaporated
3. 3
   SonstigeThe residue was purified by column chromatography on silica gel with hexane (EtOAc (95/5
4. 4
   Sonstigev/v) as eluent followed by recrystallization from the same solvent

Vorschrift

A solution of (6-iododibenzo[b,d]furan-4-yl)triphenylsilane (5.00 g, 9.05 mmol), (3-chlorophenyl) boronic acid (1.7 g, 11.3 mmol), Pd(PPh3)4 (0.105 g, 0.091 mmol) and K2CO3 (2.502 g, 18.10 mmol) in toluene (75 mL) and water (10 mL) was refluxed under nitrogen for 48 h. The organic layer was separated and the solvent was evaporated. The residue was purified by column chromatography on silica gel with hexane (EtOAc (95/5, v/v) as eluent followed by recrystallization from the same solvent to yield (6-(3-chlorophenyl)dibenzo[b,d]furan-4-yl)triphenylsilane (1.0 g, 21%) as a white solid.

Quelle