Reaktion #80064

Reaktionsgleichung

dibenzyl-[1-(4-trimethylsilanylethynyl-phenyl)-cyclopropyl]-amine

Intermediate 128

dibenzyl-[1-(4-trimethylsilanylethynyl-phenyl)-cyclopropyl]-amine

potassium carbonate

→

Dibenzyl-[1-(4-ethynylphenyl)-cyclopropyl]-amine

Lösungsmittel

methanol

Reaktionsbedingungen

Vorschrift

Using General Procedure E; dibenzyl-[1-(4-trimethylsilanylethynyl-phenyl)-cyclopropyl]-amine (Intermediate 128, 100.0 mg, 0.26 mmol) in methanol (5 mL) was treated with potassium carbonate (60.0 mg, 0.44 mmol) and stirred overnight at ambient temperature. The crude alkyne (80 mg, 99%) was used directly in the next reaction.

Quelle