Reaktion #79368

Reaktionsgleichung

(2R)-methyl 2-ethyl-7-hydroxychromane-2-carboxylate

3-bromopropyl 2-chloro-4-(4-tetrahydropyranyl)phenyl ether

→

title compound

(2R)-7-(3-(2-Chloro-4-(4-tetrahydropyranyl)phenoxy)propoxy)-2-ethylchromane-2-carboxylic acid

Reaktionsbedingungen

Vorschrift

The title compound was prepared following the procedure described in Example 5, Steps D-E employing (2R)-methyl 2-ethyl-7-hydroxychromane-2-carboxylate (Example 13, Step E) instead of ethyl 7-hydroxychromane-2-carboxylate, and 3-bromopropyl 2-chloro-4-(4-tetrahydropyranyl)phenyl ether instead of 3-bromopropyl 2-chloro-4-(2,2,2-trifluoroethoxy)phenyl ether.

Quelle