Reaktion #78967

Reaktionsgleichung

2-amino-5-bromobenzonitrile

3-chlorophenyl boronic acid

→

4-Amino-3′-chloro-biphenyl-3-carbonitrile

Reaktionsbedingungen

Vorschrift

Prepared from 2-amino-5-bromobenzonitrile and 3-chlorophenyl boronic acid according to procedure A. Off-white solid: mp 118-119° C.; 1H-NMR (DMSO-d6) δ 7.80 (d, 1H, J=2.3 Hz), 7.65-7.72 (m, 2H), 7.57 (d, 1H, J=8.0 Hz), 7.42 (t, 1H, J=7.9 Hz), 7.31 (m, 1H), 6.87 (d, 1H, J=8.7 Hz), 6.29 (br, 2H); Anal. Calc. For C13H9ClN2: C, 68.28; H, 3.97; N, 12.25: Found: C, 67.68; H, 4.06; N, 11.89.

Quelle