Reaktion #78277

ord-3a3ac0903e744d25b8303f51e43178d9

Reaktionsgleichung

O=C(O)[C@@H]1CCCN1
proline
OCC1CCCN1
2-hydroxymethylpyrrolidine
CC1CCCN1
2-methylpyrrolidine
CC1CNCC(C)N1
3,5-dimethylpiperazine
COCC1CCCN1
2-methoxymethylpyrrolidine
→
COCCNCCOC
bis-(2-methoxyethyl)amine

Edukte

O=C(O)[C@@H]1CCCN1
proline
OCC1CCCN1
2-hydroxymethylpyrrolidine
CC1CCCN1
2-methylpyrrolidine
CC1CNCC(C)N1
3,5-dimethylpiperazine
COCC1CCCN1
2-methoxymethylpyrrolidine

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Following the procedure described above, but substituting pyrrolidine with 2-hydroxymethylpyrrolidine, 2-methylpyrrolidine, 2-methoxymethylpyrrolidine, proline, 3,5-dimethylpiperazine, an bis-(2-methoxyethyl)amine provide:

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06710067B2uspto-grants-2004_03