Reaktion #78223

ord-f03d6521fe21468caf92eef68013cb3c

Reaktionsgleichung

COC(=O)c1ccc(NC(=N)N)cc1OC.O=C(O)C(F)(F)F
methyl 4-guanidino-2-methoxybenzoate trifluoroacetate
Cl
hydrochloric acid
→
COc1cc(NC(=N)N)ccc1C(=O)O.Cl
title compound
COc1cc(NC(=N)N)ccc1C(=O)O.Cl
4-Guanidino-2-methoxybenzoic acid hydrochloride

Edukte

COC(=O)c1ccc(NC(=N)N)cc1OC.O=C(O)C(F)(F)F
methyl 4-guanidino-2-methoxybenzoate trifluoroacetate
Cl
hydrochloric acid

Reagenzien

Keine

Reaktionsbedingungen

Temperatur
80°CELSIUS
Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigeThe solvent was evaporated

Vorschrift

384 mg of methyl 4-guanidino-2-methoxybenzoate trifluoroacetate was dissolved in 8 ml of 3 M hydrochloric acid, and they were stirred at 80° C. for 2.5 hours. The solvent was evaporated to obtain the title compound.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06710056B2uspto-grants-2004_03