Reaktion #78196

Reaktionsgleichung

3-hydroxybenzoic acid

iodine monochloride

→

title compound

3-Hydroxy-4-iodobenzoic acid

Lösungsmittel

acetic acid

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigethe solvent was evaporated under reduced pressure
2. 2
   WaschenThe residue was washed with 500 ml of 1% aqueous sodium thiosulfate solution twice
3. 3
   Trocknenwith 500 ml of water twice and then dried to solid at 80° C. under reduced pressure

Vorschrift

30.0 g (217 mmol) of 3-hydroxybenzoic acid was dissolved in 200 ml of acetic acid. 53.0 g (326 mmol) of iodine monochloride was added to the obtained solution at room temperature. They were stirred at 45° C. for 15 hours and then the solvent was evaporated under reduced pressure. The residue was washed with 500 ml of 1% aqueous sodium thiosulfate solution twice and with 500 ml of water twice and then dried to solid at 80° C. under reduced pressure to obtain the title compound.

Quelle