Reaktion #78194

Reaktionsgleichung

3-chloro-4,5-dimethyl-6-(pyridin-4-yl)methylpyridazine

para-methoxyaniline

→

Title compound

3-(4-methoxyanilino)-4,5-dimethyl-6-(pyridin-4-yl)methylpyridazine

Lösungsmittel

CH2Cl2 Methanol

Reaktionsbedingungen

Vorschrift

The compound is prepared from 0.070 g 3-chloro-4,5-dimethyl-6-(pyridin-4-yl)methylpyridazine and 0.129 g para-methoxyaniline in the manner described in Example 82A. Title compound is obtained after FC in CH2Cl2/Methanol 19/1. 1H-NMR (250 MHz, CDCl3): δ=8.45 (d, 2H); 7.45 (d, 2H); 7.10 (d, 2H); 6.85 (d, 2H); 6.05 (s, wide, 1H); 4.25 (s, 2H); 3.80 (s, 3H); 2.30 (s, 3H); 2.15 (s, 3H); 2.10 (s, 3H). ES-MS 321 (M+H).

Quelle