Reaktion #78148

Reaktionsgleichung

1-chloro-4-(4-pyridylmethyl)phthalazine

4-bromoaniline

→

Title compound

1-(4-Bromoanilino)-4-(4-pyridylmethyl)phthalazine

Reaktionsbedingungen

Vorschrift

A mixture of 0.384 g (1.5 mmol) 1-chloro-4-(4-pyridylmethyl)phthalazine and 0.774 g (4.5 mmol) 4-bromoaniline is heated under nitrogen atmosphere for 1.5 h at 90° C. The process is then carried out as in Example 21. Title compound is obtained after recrystallization from acetate/hexane and drying under HV (8 h at 100° C.); m.p. 201-202° C.; ESI-MS: (M+H)+=391 und 393.

Quelle