Reaktion #78026

Reaktionsgleichung

3,3′-dinitro-4,4′-diaminobiphenyl

2-furoyl chloride

hydrochloric acid

→

3,3′-dinitro-4,4′-di-2-furoylamino-biphenyl

Ausbeute 81.2%

Lösungsmittel

water

N,N-dimethylformamide

water

pyridine

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeIn a 500 ml separable flask equipped with a stirrer, a reflux condenser
2. 2
   workup.ADDITIONAfter the addition
3. 3
   Temperaturthe reaction solution was warmed to the room temperature
4. 4
   Sonstigethe solid substance was separated by filtration
5. 5
   WaschenThe obtained solid substance was washed well with water
6. 6
   Sonstigedried in a reduced pressure

Vorschrift

In a 500 ml separable flask equipped with a stirrer, a reflux condenser cooled with water, a thermometer and a dropping funnel, 10.96 g of 3,3′-dinitro-4,4′-diaminobiphenyl was dissolved into 200 ml of N,N-dimethylformamide and then 20 ml of pyridine was added to the solution. While the prepared solution was cooled at 3 to 14° C., 12.53 g of 2-furoyl chloride was added dropwise to the solution. After the addition was completed, the reaction solution was warmed to the room temperature and stirred for further 5 hours. Then, 80 ml of 2N hydrochloric acid and 100 ml of water were added to the solution and the solid substance was separated by filtration. The obtained solid substance was washed well with water and dried in a reduced pressure to obtain 15.0 g of 3,3′-dinitro-4,4′-di-2-furoylamino-biphenyl. The yield was 81%.

Quelle