Reaktion #77575

Reaktionsgleichung

1,4-bis[5-[3,5-bis(methoxymethyl)phenyl]-2-pyridyl]hexahydro-1,4-diazepine

hydrochloric acid

→

title compound

Ausbeute 92.0%

1,4-Bis[5-[3,5-bis(methoxymethyl)phenyl]-2-pyridyl]hexahydro-1,4-diazepine Dihydrochloride

Ausbeute 92.0%

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Einengenthe reaction mixture was concentrated under reduced pressure
2. 2
   workup.ADDITIONEthanol (5.0 mL) was added to the residue
3. 3
   Einengenthe resulting mixture was concentrated under reduced pressure

Vorschrift

To a solution of 1,4-bis[5-[3,5-bis(methoxymethyl)phenyl]-2-pyridyl]hexahydro-1,4-diazepine (51.9 mg, 0.0892 mmol) in ethanol (5.0 mL) was added 1.0 M hydrochloric acid (0.21 mL, 0.21 mmol), and the reaction mixture was concentrated under reduced pressure. Ethanol (5.0 mL) was added to the residue and the resulting mixture was concentrated under reduced pressure to yield the title compound as a colorless amorphous powder (47.8 mg, yield: 92%).

Quelle