Reaktion #77364

ord-47b00df6f2544c8daca5f62fb0375b43

Reaktionsgleichung

COc1ccc(-c2ccc3c(c2)NC(=O)C3)cc1
6-(4-Methoxy-phenyl)-1,3-dihydro-indol-2-one
O=Cc1cc2cc(OCCN3CCOCC3)ccc2[nH]1
5-(2-morpholin-4-yl-ethoxy)-1H-indole-2-carbaldehyde
→
COc1ccc(-c2ccc3c(c2)NC(=O)C3=Cc2cc3cc(OCCN4CCOCC4)ccc3[nH]2)cc1
title compound
COc1ccc(-c2ccc3c(c2)NC(=O)C3=Cc2cc3cc(OCCN4CCOCC4)ccc3[nH]2)cc1
6-(4-Methoxy-phenyl)-3-[5-(2-morpholin-4-yl-ethoxy)-1H-indol-2-ylmethylene]-1,3-dihydro-indol-2-one

Edukte

COc1ccc(-c2ccc3c(c2)NC(=O)C3)cc1
6-(4-Methoxy-phenyl)-1,3-dihydro-indol-2-one
O=Cc1cc2cc(OCCN3CCOCC3)ccc2[nH]1
5-(2-morpholin-4-yl-ethoxy)-1H-indole-2-carbaldehyde

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

6-(4-Methoxy-phenyl)-1,3-dihydro-indol-2-one was condensed with 5-(2-morpholin-4-yl-ethoxy)-1H-indole-2-carbaldehyde to give the title compound.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06706709B2uspto-grants-2004_03