Reaktion #76874

ord-4ee9c84cc4ce4553a746de16cbffe16b

Reaktionsgleichung

COc1ccc2c(c1)CCNC2Cc1ccc(OC)c(OC)c1
1-(3,4-dimethoxy-benzyl)-6-methoxy-1,2,3,4-tetrahydroisoquinoline
O=C(Br)CBr
2-bromoacetyl bromide
NC1CCc2ccccc21
1-amino-indane
→
COc1ccc2c(c1)CCN(CC(=O)NC1CCc3ccccc31)C2Cc1ccc(OC)c(OC)c1
2-[1-(3,4-Dimethoxy-benzyl)-6-methoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-(indan-1-yl)-acetamide

Edukte

COc1ccc2c(c1)CCNC2Cc1ccc(OC)c(OC)c1
1-(3,4-dimethoxy-benzyl)-6-methoxy-1,2,3,4-tetrahydroisoquinoline
O=C(Br)CBr
2-bromoacetyl bromide
NC1CCc2ccccc21
1-amino-indane

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

prepared by reaction of 1-(3,4-dimethoxy-benzyl)-6-methoxy-1,2,3,4-tetrahydroisoquinoline and 2-bromoacetyl bromide with 1-amino-indane

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06703392B2uspto-grants-2004_03