Reaktion #76493

ord-18ce3a370f5c47b09af3e24cfb90cbdf

Reaktionsgleichung

Nc1ccc2ncccc2c1N
5,6-quinolinediamine
O.O=C(O)C(=O)O
oxalic acid hydrate
→
O=c1[nH]c2ccc3ncccc3c2[nH]c1=O
solid
Ausbeute 83.0%
O=c1[nH]c2ccc3ncccc3c2[nH]c1=O
1,4-Dihydropyrido[3,2-f]quinoxaline-2,3-dione
Ausbeute 83.0%

Edukte

Nc1ccc2ncccc2c1N
5,6-quinolinediamine
O.O=C(O)C(=O)O
oxalic acid hydrate

Reagenzien

Keine

Lösungsmittel

Cl
HCl

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    Temperaturwas heated
  2. 2
    Temperaturat reflux for 2 hours

Vorschrift

A mixture of 5,6-quinolinediamine (11.3 g, 0.071 mol) and oxalic acid hydrate (17.9 g, 0.142 mol) in 200 mL 2N HCl was heated at reflux for 2 hours. The solid (12.3 g, 83% yield) was collected by filtration and washed consecutively with water and ether.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06703391B2uspto-grants-2004_03