Reaktion #76465

ord-5cbc24fd922548b9929f84fb3faf31eb

Reaktionsgleichung

Cc1ccc2c(=O)c3ccccc3n(CCCN3C(=O)c4ccccc4C3=O)c2c1C
3,4-dimethyl-10-(3-phthalimidopropyl)-9-acridone
O=C(Cl)C(=O)Cl
oxalyl chloride
→
Cc1ccc2c(Cl)c3ccccc3[n+](CCCN3C(=O)c4ccccc4C3=O)c2c1C.[Cl-]
title compound
Cc1ccc2c(Cl)c3ccccc3[n+](CCCN3C(=O)c4ccccc4C3=O)c2c1C.[Cl-]
3,4Dimethyl-9-chloro-10-(3-phthalimidopropyl)acridinium Chloride

Edukte

Cc1ccc2c(=O)c3ccccc3n(CCCN3C(=O)c4ccccc4C3=O)c2c1C
3,4-dimethyl-10-(3-phthalimidopropyl)-9-acridone
O=C(Cl)C(=O)Cl
oxalyl chloride

Reagenzien

Keine

Lösungsmittel

ClCCl
dichloromethane

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigeAfter evaporating the excessive oxalyl chloride and dichloromethane under reduced pressure

Vorschrift

A mixture of 1.0 g of 3,4-dimethyl-10-(3-phthalimidopropyl)-9-acridone with 340 ml of oxalyl chloride was stirred at room temperature in 100 ml of dichloromethane for 30 min. After evaporating the excessive oxalyl chloride and dichloromethane under reduced pressure, 1.1 g of the title compound was obtained.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06703388B2uspto-grants-2004_03