Reaktion #7618
ord-eaa1edd7c46b4a0391401b349c4af6d3
Reaktionsgleichung
acetylchloride
2-amino-5-nitropyridine
cyclohexylisonitrile
pyridine-2-carbaldehyde
→
1-acetyl-3-cyclohexylamino-6-nitro-2-pyridin-2-yl-imidazo[1,2-a]pyridin-1-ium chloride
Reagenzien
Keine
Lösungsmittel
Reaktionsbedingungen
Detaillierte Bedingungen
See reaction.notes.procedure_details.
Vorschrift
Example 16 was carried out in accordance with the general directions for synthesis in process step a) from 1.0 ml (0.1 mmol) 2-amino-5-nitropyridine (0.1 M, DCM), 0.575 ml (0.115 mmol) cyclohexylisonitrile solution (0.2 M, DCM), 0.500 ml (0.15 mmol) pyridine-2-carbaldehyde solution (0.3 M, DCM) and 10 μl perchloric acid (w=20%) and in process step c) and d) by reacting the resultant reaction product with 0.4 mmol acetylchloride.